Beilstein J. Nanotechnol.2022,13, 641–652, doi:10.3762/bjnano.13.56
the preparation of berberine (BBR) in nanoformulation to enhance its solubility and increase its antibacterial effectiveness against hospital-acquired infections. BBR nanoparticles (BBR NPs) were formed by antisolventprecipitation (ASP) using glycerol as a safe organic solvent. UV–vis absorption
bacterial cells and severely damaged the cell walls. Therefore, BBR NPs prepared by ASP appear to be a potential candidate for the treatment of bacterial pathogens.
Keywords: antibacterial activity; antisolventprecipitation (ASP); berberine nanoparticles (BBR NPs); glycerol; solubility; Introduction
(EPN) and antisolventprecipitation (ASP)). Although top-down technologies have a high yield, they are energy-consuming and the obtained crystal size is inhomogeneous [26][27]. The ASP technique can modify crystal formation and particle size distributions [5]. Sahibzada et al. [26] reported that BBR
PDF
Figure 1:
UV–vis spectra of BBR and BBR NPs in distilled water at a concentration of 2.0 mg/mL.